MEDIMMUNE SAMPLE PURIFICATION ROBOT
System Overview.
The sample purification robot was installed at Medimmune, Cambridge in 2007 and was designed to replace an existing system that required a lot of user intervention during the purification process. The robot is used as part of the development of human monoclonal antibody therapeutics and performs the initial sample purification by passing a number of reagents through SPE columns followed by the sample. The resultant purified sample is collected in Eppendorf tubes ready for aliquoting. The final samples are aliquoted into Micronics tubes, microtitre plates and PCR well plates. The robot runs 3 batches of 48 samples over a 24 hour period.
Key Features.
Capacity for Falcon Input Tubes
Capacity for 144 50ml Falcon input tubes
Capacity For Reagents in Litre Containers
Capacity for 10 reagents in 20 litre containers
SPE Column Sizes
6 sets of various size SPE columns (1ml, 3ml and 5ml) are stored in the robot
Syringes
2 sets of syringes (10ml and 50ml) are automatically selected
Automated Filtration & Diluent Waste
Automated filtration and diluent waste management
Medimmune LIMS
Integration with the Medimmune LIMS
LIMS Input Sample Infomation
Identification of input sample information via LIMS
Dilution Volumes & Diluent Selection
Fully configurable dilution volumes and diluent selection for each stage
